Rossella Cannarella

Dottorando - Tutor: Aldo Eugenio Calogero
Email: rossella.cannarella@phd.unict.it
Telefono: +39.3895986660


Curriculum

CV 

 

Attività di ricerca

Le linee di ricerca portate avanti dalla Dott.ssa Cannarella possono essere riassunte in:

  • Terapia con FSH per il trattamento del maschio infertile: la Dott.ssa Cannarella ha pubblicato in qualità di primo autore la prima meta-analisi comparativa degli effetti della terapia con FSH sui parametri spermatici convenzionali nei pazienti affetti da oligozoospermia, dimostrandone per la prima volta l’efficacia dose-dipendente (doi: 10.4103/aja.aja_42_19). E’impegnata in altre ricerca in vitro relative all’effetto diretto dell’FSH sugli spermatozoi umani.  
  • Effetto del GH/IGF1 sulla funzione testicolare: la Dott.ssa ha prodotto numerosi articoli che documentano il ruolo del GH/IGF1 sulla funzione testicolare nell’animale (doi: 10.1530/EC-17-0158, doi: 10.1111/andr.12444, doi: 10.3390/jcm8050577, doi: 10.3390/jcm8060811) e nell’uomo (doi: 10.3389/fendo.2021.619895). Si è occupata anche di articoli inerenti la funzione testicolare in età pediatrica (doi: 10.1007/s12020-018-1670-9; doi: 10.3390/jcm8091410; doi: 10.3390/jcm9030780; doi: 10.3390/jcm8050636). Recentemente, ha prodotto uno studio in vitro che documenta gli effetti del GH, dell’IGF1 e dell’AMH sulla migrazione e secrezione dei neuroni GnRH secernenti (doi: 10.3390/ijms22052445). Questa linea di ricerca potrebbe essere utile per l’identificazione precoce di una disfunzione testicolare in età pediatrica, inclusi i possibili fattori eziologici di quest’ultima.
  •  Genetica dell’infertilità maschile: i difetti monogenici della spermatogenesi rappresentano una causa di infertilità maschile recentemente nosografata, alla quale la Dott.ssa ha contribuito con i seguenti lavori: doi: 10.3389/fgene.2020.00974; doi: 10.4103/aja.aja_25_20; doi: 10.1007/s00439-019-01974-1; doi: 10.3389/fendo.2020.605237; doi: 10.3390/life10100242.
  • Equivalente maschile della sindrome dell’ovaio micropolicistico: l’eziologia poligenica della PCOS rendono verosimile la possibilità di ereditare i geni predisponenti allo sviluppo della PCOS nella donna anche nell’uomo. I familiari maschi di donne con PCOS mostrano una prevalenza maggiore di alopecia androgenetica e un aumentato rischio di sviluppare diabete e malattie cardiovascolari (doi: 10.1155/2020/1942126; doi: 10.1007/s40618-017-0728-5; doi: 10.1016/j.mehy.2020.109601). Tali uomini inoltre, mostrano un pattern ormonale “PCOS-like” (doi: 10.1038/s41598-017-08528-3).

Progetto di ricerca:  Espressione di fattori di crescita embrio-placentare a livello spermatico: Possibili target diagnostici?

Parole chiave: Infertilità maschile; FSH; ormone follicolo-stimolante; GH; IGF1; IGF2; ormone anti-Mülleriano; AMH; equivalente maschile della PCOS; cellule del Sertoli; spermatozoi.

Pubblicazioni

1. Condorelli R, Calogero AE, Vicari E, Mongioì L, Burgio G, Cannarella R, Giacone F, Iacoviello L, Morgia G, Favilla V, Cimino S, La Vignera S 2014 Reduced seminal concentration of CD45pos cells after follicle-stimulating hormone treatment in selected patients with idiopatic oligoasthenoteratozoospermia. Int J Endocrinol 2014:372060. DOI: 10/1155/2014/372060. Scopus 2-s2.0-84893852163. WOS: 000330391200001.

2. Cannarella R, Scilletta S, Scilletta R, Magro G, Calogero AE. Resolution of primary hyperparathyroidism following surgical removal of cervical thymus. Case Reports in Internal Medicine. 2017; 4(2). DOI: https://doi.org/10.5430/crim.v4n2p5.
3. Cannarella R, Calogero AE, Condorelli R, Vicari E, La Vignera S 2014 La funzione gonadica nell’adolescente obeso. In: Foresta C, Lenzi A, Ferlin A, Garolla A (Eds), Gli scenari della fertilità umana tra ambiente e società. Cleup Editrice, Padova, p. 99-114. ISBN 9788867871841.
4. Tamburino L, La Vignera S, Tomaselli V, Condorelli RA, Cannarella R, Mongioì LM, Calogero AE 2017 The -29 G/A FSH receptor gene polymorphism is associated with higher FSH and LH levels in normozoospermic men. J Assist Reprod Genet 34:1289-1294. DOI: 10.1007/s10815-017-0970-y. Scopus 2-s2.0-85020499531. WOS: 000412663100008.
5. Cannarella R, Condorelli RA, Mongioì LM, La Vignera S, Calogero AE 2018 Does a male equivalent of polycystic ovarian syndrome exist? J Endocrinol Invest 41:49-57. DOI: 10.1007/s40618-017-0728-5. Scopus 2-s2.0-85023781555. WOS:000419489200005.
6. Cannarella R, Condorelli RA, La Vignera S, Calogero AE 2017 Glycolipid and hormonal profiles in young men with early-onset androgenetic alopecia: a meta-analysis. Sci Rep 7:7801. DOI:10.1038/s41598-017-08528-3. Scopus 2-s2.0-85051538584. WOS: 000407400500033.
7. Cannarella R, Mattina T, Condorelli RA, Mongioì LM, Pandini G, La Vignera S, Calogero AE 2017 Chromosome 15 structural abnormalities: effect on the IGF1R gene expression and function. Endocr Connect 6:528-539. DOI: 10.1530/EC-17-0158. Scopus 2-s2.0-85029691631. WOS: 000411647000014.
8. Condorelli RA, Calogero AE, Di Mauro M, Mongioì LM, Cannarella R, Rosta G, La Vignera S 2018 Androgen excess and metabolic disoderders in women with PCOS: beyond the body mass index. J Endocrinol Invest 41:383-388.DOI: 10.1007/s40618-017-0762-3. Scopus 2-s2.0-85029768701. WOS: 000427608300001.
9. Salemi M, Cimino L, Marino M, Cannarella R, Condorelli RA, Romano C, La Vignera S, Calogero AE 2018 Next generation sequencing expression profiling of mitochondrial subunits in men with Klinefelter syndrome. Int J Med Sci 15:31-35. DOI: 10.7150/ijms.21075. Scopus 2-s2.0-85038893112. WOS: 000422696900005.
10. Cannarella R, Condorelli RA, La Vignera S, Calogero AE 2018 Effects of the insulin-like growth factor system on testicular differentiation and function: a review of the literature. Andrology 6:3-9. DOI: 10.1111/andr.124444. Scopus 2-s2.0-85036502945. WOS: 000418797400002.
11. Cimino L, Salemi M, Cannarella R, Condorelli R, Giurato G, Marchese G, La Vignera S, Calogero AE 2017 Decreased miRNA expression in Klinefelter syndrome. Sci Rep 7:16672. DOI: 10.1038/s41598-017-16892-3. Scopus 2-s2.0-85036638864. WOS: 000416891400074.
12. Cannarella R, Burgio R, La Vignera S, Vicari ES, Calogero AE 2018 Anejaculation in a patient with Charcot-Marie-Tooth. Asian J Androl 20:529-530; DOI: 10.4103/aja.aja_75_17. Scopus 2-s2.0-85054955944. WOS: 000447611700021.
13. Calogero AE, Burgio G, Condorelli RA, Cannarella R, La Vignera S 2019 Lower urinary tract symptoms/benign prostatic hyperplasia and erectile dysfunction: from physiology to clinical aspects. Aging Male 21:261-271. DOI: 10.1080/13685538.2018.1430758. Scopus 2-s2.0-85056532690. WOS: 000450637900006.
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14. Calogero AE, Burgio G, Condorelli RA, Cannarella R, La Vignera S 2019 Treatment of lower urinary tract symptoms/benign prostatic hyperplasia and erectile dysfunction. Aging Male 21:272-280. DOI: 10.1080/13685538.2018.1432586. Scopus 2-s2.0-85056488587. WOS: 000450637900007.
15. Calogero AE, Burgio G, Condorelli RA, Cannarella R, La Vignera S 2019 Epidemiology and risk factors of lower urinary tract symptoms/benign prostatic hyperplasia and erectile dysfunction. Aging Male 22:12-19. DOI: 10.1080/13685538.2018.1434772. Scopus 2-s2.0-85060138132. WOS: 000455999800002.
16. Bosco D, Cammarata A, Cannarella R, Latino R, Lanteri R, Di Cataldo A, Calogero A 2017 Thyroid hemiagenesis associated with multinodular goiter and Hashimoto’s thyroiditis. G Chir. 38:291-294. Scopus 2-s2.0-85042301086.
17. La Vignera S, Rago R, Condorelli RA, Cannarella R, Gallo M, Calogero AE 2018 Fattori di rischio dell’infertilità maschile. In: Foresta C (Ed) e il contributo di Viora E, La Medicina della Riproduzione Umana: Il percorso clinico e diagnostico condiviso. Editeam Gruppo Editoriale, Cento (FE). p. 4-15. ISBN 88-6135-198-0 - 978-88-6135-198-1.
18. Calogero AE, Condorelli RA, Cannarella R, Alamo A, Cimino L, Compagnone M, La Vignera S 2018 Influenza delle patologie sistemiche ed endocrine sulla fertilità maschile. In: Foresta C (Ed) e il contributo di Viora E, La Medicina della Riproduzione Umana: Il percorso clinico e diagnostico condiviso. Editeam Gruppo Editoriale, Cento (FE). p. 69-87. ISBN 88-6135-198-0 - 978-88-6135-198-1.
19. Rago R, Gallo M, La Vignera S, Cannarella R, Licata E, Condorelli RA, Calogero AE 2018 Aging maschile: quale ruolo nella spermatogenesi e nelle tecniche di procreazione medicalmente assistita. In: Foresta C (Ed) e il contributo di Viora E, La Medicina della Riproduzione Umana: Il percorso clinico e diagnostico condiviso. Editeam Gruppo Editoriale, Cento (FE). p. 95-103. ISBN 88-6135-198-0 - 978-88-6135-198-1.
20. Condorelli RA, Cannarella R, Calogero AE, La Vignera S 2018 Valutazione della funzione testicolare in età pediatrica e prepuberale. L’Endocrinologo 19:136–141. DOI: 10.1007/s40619-018-0446-z.
21. Cannarella R, Burgio G, Vicari ES, La Vignera S, Condorelli RA, Calogero AE 2018 Urogenital dysfunction in male patients with Charcot-Marie-Tooth: a systematic review. Aging Male 31:1-5. DOI: 10.1088/13685538.2018.1791543. Scopus 2-s2.0-85077303201.
22. Sessa F, Messina G, Russo R, Salerno M, Castruccio Castracani C, Distefano A, Li Volti G, Calogero AE, Cannarella R, Mongioì LM, Condorelli RA, La Vignera S 2018 Consequences on aging process and human wellness of generation of nitrogen and oxygen species during strenuous exercise. Aging Male 27:1-9. DOI: 10.1080/13685538.2018.1482866. Scopus 2-s2.0-85055098821. WOS: 3A000509675100004.
23. Condorelli RA, Cannarella R, Calogero AE, La Vignera S 2018 Evaluation of testicular function in prepubertal children. Endocrine 62:274-280. DOI: 10.1007/s12020-018-1670-9. Scopus 2-s2.0-85049576352. WOS: 000449306400002.
24. La Vignera S, Condorelli RA, Cannarella R, Calogero AE 2018 The advantages of proteomic investigation in the management of male accessory gland infection: a response to Grande et al. Am J Reprod Immunol 80:e13063. DOI: 10.1111/aji.13063. Scopus 2-s2.0-85054593075. WOS: 000451434800006.
25. Giacone F, Cannarella R, Mongioì LM, Alamo A, Condorelli RA, Calogero AE, La Vignera S 2018 Epigenetics of male infertility: effects on assisted reproductive techniques. World J Men’s Health. In press. DOI: 10.5534/wj,h.180071. Scopus 2-s2.0-85075157143. WOS: 000465475300004.
26. Duca Y, Calogero AE, Cannarella R, Condorelli RA, La Vignera S 2019 Current and emerging medical therapeutic agents for idiopathic male infertility. Expert Opin Pharmacother 20:55-67. DOI: 10.1080/14656566.2018.1543405. Scopus 2-s2.0-85059252100. WOS: 000454521900008.
27. Salemi M, Cannarella R, Condorelli RA, Cimino L, Ridolfo F, Giurato G, Romano C, La Vignera S, Calogero AE 2019 Evidence for long non-coding RNA GAS5 upregulation in patients with Klinefelter syndrome. BMC Med Genet 20:4. DOI: 10.1186/s12881-018-0744-0. Scopus 2-s2.0-85059499147. WOS: 000455013200001.
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28. Cannarella R, Condorelli RA, Duca Y, La Vignera S, Calogero AE 2019 New insights into the genetics of spermatogenic failure: a review of the literature. Hum Genet 138:125-140. DOI: https://doi.org./10.1007/s00439-019-01974-1. Scopus 2-s2.0-85060196483. WOS: 000458432800002.
29. La Vignera S, Condorelli RA, Cannarella R, Di Mauro M, Calogero AE 2017 Diabetes mellitus: mechanisms of male reproductive impairment. Giornale Italiano di Diabetologia e Metabolismo 37:289-294.
30. Cannarella R, Condorelli RA, Mongioì LM, Giacone F, Calogero AE, La Vignera S 2019 Management of male accessory gland inflammations: a response to Haidl et al. Andrologia 51:e13261. DOI: 10.1111/and.13261. Scopus 2-s2.0-85062768470. WOS: 000471975000024.
31. Duca Y, Calogero AE, Cannarella R, Giacone F, Mongioì LM, Condorelli RA, La Vignera S 2019 Erectile dysfunction, physical activity, and physical exercise: recommendations for clinical practice. Andrologia 51:e13264. DOI: 10.1111/and.13264. Scopus 2-s2.0-85062964473. WOS: 000471975000025.
32. La Vignera S, Condorelli RA, Duca Y, Mongioì LM, Cannarella R, Giacone F, Calogero AE 2019 FSH therapy for idiopathic male infertility: four schemes are better than one. Aging Male [Epub ahead of print]. DOI: 10.1080/13685538.2019.1590696. Scopus 2-s2.0-85063871092. WOS: 000464634900001.
33. Cannarella R, La Vignera S, Condorelli RA, Mongioì LM, Calogero AE 2020 FSH dosage effect on conventional sperm parameters: A meta-analysis of randomized controlled studies. Asian J Androl 22:309-316. DOI: 10.4103/aja.aja_42_19. Scopus 2-s2.0-85083544189. WOS:000530722200014.
34. La Vignera S, Cannarella R, Duca Y, Barbagallo F, Burgio G, Compagnone M, Di Cataldo A, Calogero AE, Condorelli RA 2019 Hypogonadism and sexual dysfunction in testicular tumor survivors: A systematic review. Front Endocrinol 10:264. DOI. 10.3389/fendo.2019.00264. Scopus 2-s2.0-85067984991. WOS: 000467303500001.
35. Cannarella R, Calogero AE, Condorelli RA, Giacone F, Mongioì LM, La Vignera S 2019 Non-hormonal treatment for male infertility: the potential role of Serenoa repens, selenium and lycopene. Eur Rev Med Pharmacol Sci 23:3112-3120. DOI: 10.26355/eurrev_201904_17595. Scopus 2-s2.0-85064408319. WOS: 000466386900050.
36. Condorelli RA, Cannarella R, Bonforte S, Calogero AE, La Vignera S 2019 Valutazione della funzione testicolare in età pediatrica e prepuberale. Il Pediatra, giugno 2019, pag. 44-49.
37. Alamo A, Condorelli RA, Mongioì LM, Cannarella R, Giacone F, Calabrese V, La Vignera S, Calogero AE 2019 Environment and male fertility: effects of benzo-α-pyrene and resveratrol on human sperm function in vitro. J Clin Med 8:561. DOI: 10.3390/jcm8040561. WOS: 000467500200146.
38. Cannarella R, Arato I, Condorelli RA, Luca L, Barbagallo F, Alamo A, Bellucci C, Lilli C, La Vignera S, Calafiore R, Mancuso F, Calogero AE 2019 The IGF1R is involved in FSH signaling in porcine neonatal Sertoli cells. J Clin Med 8:577. DOI: 10.3390/jcm8050577. WOS: 000470992500012.
39. Condorelli RA, Calogero AE, Cannarella R, Giacone F, Mongioì LM, Cimino L, Aversa A, La Vignera S 2019 Poor efficacy of L-acetyl-carnitine in the treatment of asthenozoospermia in patients with type 1 diabetes. J Clin Med 8:585. DOI:10.3390/jcm8050585. WOS: 000470992500020.
40. La Vignera S, Condorelli RA, Cannarella R, Calogero AE 2019 Thyroid prostate axis. Does it really exist? World J Mens Health 37:257-260. DOI: 10.5534/wjmh.190060. Scopus 2-s2.0-85078952360. WOS: 000482196700001.
41. Cannarella R, Condorelli RA, Mongioì LM, Barbagallo F, Calogero AE, La Vignera S 2019 Effects of the selective estrogen receptor modulators for the treatment of male infertility: A systematic-review and meta-analysis. Expert Opin Pharmacother 20:1517-1525. DOI: 10.1080/14656566.2019.1615057. Scopus 2-s2.0-85066881262. WOS: 000469578700001.
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42. La Vignera S, Condorelli RA, Cimino L, Cannarella R, Giacone F, Calogero AE 2019 Early identification of Sertoli cell dysfunction in prepubertal and transitions age: it it time? J Clin Med 8:636. DOI: 10.3390/jcm8050636. WOS: 000470992500071.
43. Duca Y, Calogero AE, Condorelli RA, Vicari E, Cannarella R, Favilla V, Vetri M, Certo M, Sidoti G, Panella P, Lanzafame F, Giammusso B, La Vignera S 2019 Early male aging or poor clinical consideration for males in IVF centers? An original study. Aging Male Online: 28 May 2019. DOI: 10.1080/13685538.2019.1618260.
44. Condorelli RA, La Vignera S, Mongioì LM, Alamo A, Giacone F, Cannarella R, Calogero AE 2019 Thyroid hormones and spermatozoa: in vitro effects on sperm mitochondria, viability and DNA integrity. J Clin Med 8:756. DOI: 10.3390/jcm8050756. WOS:000470992500191.
45. Mongioì LM, Condorelli RA, Barbagallo F, Cannarella R, La Vignera S, Calogero AE 2019 Accuracy of the low-dose ACTH stimulation test for adrenal insufficiency diagnosis: a re-assessment of the cut-off value. J Clin Med 8:806. DOI: 10.3390/jcm8060806. WOS: 000475349300050.
46. Cannarella R, Arato I, Condorelli RA, Mongioì LM, Lilli C, Bellucci C, La Vignera S, Luca G, Mancuso F, Calogero AE 2019 Effects of insulin on porcine neonatal Sertoli cell responsiveness to FSH in-vitro. J Clin Med 8:209. DOI: 10.3390/jcm8060809. WOS: 000475349300053.
47. La Vignera S, Condorelli RA, Cannarella R, Giacone F, Mongioì L, Scalia G, Favilla V, Russo GI, Cimino S, Morgia G, Calogero AE 2019 High rate of detection of ultrasound signs of prostatitis in patients with HPV-DNA persistence on semen: role of ultrasound in HPV-related male accessory gland infection. J Endocrinol Invest 42:1459-1465. DOI: 10.1007/s40618-019-01069-8. Scopus 2-s2.0-85067067420. WOS: 3A000494824400007.
48. La Vignera S, Condorelli RA, Cannarella R, Giacone F, Calogero AE 2019 Arterial erectile dysfunction is an early sign of vascular damage: the importance for the prevention of cardiovascular health. Ann Transl Med 7 (Suppl 3):S124. DOI: 10.21037/atm.2019.05.61. WOS: 000483693200050.
49. Cannarella R, Mancuso F, Condorelli RA, Arato I, Mongioì LM, Giacone F, Lilli C, Bellucci C, La Vignera S, Calafiore R, Luca L, Calogero AE 2019 Effects of GH and IGF1 on basal and FSH-modulated porcine Sertoli cells in-vitro. J Clin Med 8:811. DOI: 10.3390/jcm8060811. WOS: 000475349300055.
50. Cannarella R, Condorelli RA, La Vignera S, Bellucci C, Luca G, Calafiore R, Calogero AE 2020 IGF2 and IGF1R mRNAs are detectable in human spermatozoa. World J Men’s Health 38:545-551. DOI: 10.5534/wjmh.190070. Scopus 2-s2.0-85081029078. WOS:000572091100010.
51. La Vignera S, Condorelli RA, Cannarella R, Cimino L, Mongioì LM, Duca Y, Giacone F, Calogero AE 2019 Testosterone levels after treatment with urofollitropin in infertile patients with idiopathic mild reduction of testicular volume. Endocrine 66:381-385. DOI: 10.1007/s12020-019-01983-0. Scopus 2-s2.0-85068151686 WOS: 000509108100027.
52. La Vignera S, Condorelli RA, Duca Y, Cannarella R, Giacone F, Calogero AE 2019 FSH treatment for normogonadotropic male infertility: a sinergistic role for metformin? Eur Rev Med Pharmacol Sci 23:5994-5998. Scopus 2-s2.0-85068915796. WOS: 000478566500052.
53. Cannarella R, Condorelli RA, La Vignera S, Calogero AE 2019 Commentary: Molecular mechanismis of action of FSH. Front Endocrinol 10:593. DOI: 10.3389/fendo.2019.00593. Scopus 2-s2.0-85072726086. WOS: 000482798800001.
54. La Vignera S, Condorelli RA, Cannarella R, Giacone F, Mongioì LM, Cimino L, Defeudis G, Mazzilli R, Calogero AE 2019 Urogenital infections in patients with diabetes mellitus: beyond the conventional aspects. Int J Immunopathol Pharmacol 33:1-6. DOI: 10.1177/2058738419866582. Scopus 2-s2.0-85077303201. WOS: 000486727600001.
55. Cannarella R, Liuzzo C, Mongioì LM, Condorelli RA, La Vignera S, Bellanca S, Calogero AE 2019 Decreased total sperm counts in habitants of highly polluted areas of Eastern Sicily, Italy. Environ Sci Pollut
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Res 26:31368-31373. DOI: 10.1007/s11356-019-06248-x. Scopus 2-s2.0-85071490048. WOS: 000494047900071.
56. Guerri G, Maniscalchi T, Barati S, Busetto GM, Del Giudice F, De Berardinis E, Cannarella R, Calogero AE, Bertelli M 2019 Male infertility. Acta Biomed 90 (Supplement 10):62-67. DOI: 10.23750/abm.v90i10-S.8762. Scopus 2-s2.0-85072848003.
57. Cannarella R, Calogero AE, Condorelli RA, Giacone F, Aversa A, La Vignera S 2019 Management and treatment of varicocele in children and adolescents: an endocrinologic perspective. J Clin Med 8:1410. DOI: 10.3390/jcm8091410. WOS: 000489184200144.
58. Cannarella R, Barbagallo F, Condorelli RA, Aversa A, La Vignera S, Calogero AE 2019 Osteoporosis from an endocrine perspective: The role of hormonal changes in the elderly. J Clin Med 8:1564. DOI: 10.3390/jcm8101564. WOS: 000498398500062.
59. La Vignera S, Condorelli RA, Calogero AE, Cannarella R, Mongioì LM, Duca Y, Cimino L, Giacone F, Aversa A 2020 Symptomatic late-onset hypogonadism but normal total testosterone: the importance of testosterone annual decrease velocity. Ann Transl Med 8:163. doi: 10.21037/atm.2019.11.48. WOS: 000520850100015.
60. Cannarella R, Condorelli RA, La Vignera S, Calogero AE 2020 Terapia medica dell’infertilità maschile L’Endocrinologo (in press). DOI: 10.1007/s40619-020-00654-x.
61. Cannarella R, Condorelli RA, La Vignera S, Calogero AE 2020 Infertilità maschile, un problema pediatrico? Edit Symposia Pediatria & Neonatologia 1:1-9.
62. Cannarella R, Condorelli RA, Dall’Oglio F, La Vignera S, Mongioì LM, Micali G, Calogero AE 2020 Increased DHEAS and decreased total testosterone serum levels in a subset of men with early-onset androgenetic alopecia: Does a male PCOS-equivalent exist? Int J Endocrinol 2020:1942126. DOI: 10.1155/2020/1942126. Scopus 2-s2.0-85081991874.
63. Barbagallo F, La Vignera S, Cannarella R, Calogero AE, Condorelli RA 2020 Evaluation of sperm mitochondrial function: a key organelle for sperm motility. J Clin Med 9:363. DOI: 10.3390/jcm9020363. WOS: 3A000518823000075.
64. Cannarella R, La Vignera S, Barbagallo F, Condorelli RA, Calogero AE 2020 Male polycystic ovary syndrome equivalent: A response to Di Guardo et al. Med Hypotheses 137:109601. DOI: 10.1016/j.mehy.2019.03.003. Scopus 2-s2.0-85078497230.
65. Cannarella R, Lanzafame F, Condorelli RA, Calogero AE, La Vignera S 2020 Antioxidants in the medical and surgical management of male infertility. In Parekattil SJ, Agarwal A (Eds), Male Infertility: Contemporary Clinical Approaches, Andrology, ART and Antioxidants, 2nd Edition. Pages 805-816. DOI: 10.1007/978-3-030-32300-4_64. ISBN 978-1-4614-3335-4.
66. Cannarella R, Condorelli RA, Mongioì LM, La Vignera S, Calogero AE 2020 Molecular biology of spermatogenesis: novel targets of apparently idiopathic male infertility. Int J Mol Sci 21:1728. DOI: 10.3390/ijms21051728. Scopus 2-s2.0-85080993828. WOS: 000524908500179.
67. Cannarella R, Calogero AE, Aversa A, Condorelli RA, La Vignera S 2020 Is there a role for levo-thyroxine for the treatment of arterial erectile dysfunction? The clinical relevance of the mean platelet volume. J Clin Med 9:742. DOI: 10.3390/jcm9030742. WOS: 000527278800131.
68. La Vignera S, Cannarella R, Condorelli RA, Calogero AE 2020 Disorders of Puberty: Endocrinology of the pre-pubertal testis. J Clin Med 9:780 - DOI: 10.3390/jcm9030780. WOS: 000527278800169.
69. Torre F, Calogero AE, Condorelli RA, Cannarella R, Aversa A, La Vignera S 2020 Effects of oral contraceptives on thyroid function and vice versa. J Endocrinol Invest 43:1181-1188. DOI: 10.1007/s40618-020-01230-8. Scopus 2-s2.0-85082973206. WOS: 000521882000002.
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70. Cannarella R, Condorelli RA, Paolacci S, Barbagallo F, Guerri G, Bertelli M, La Vignera S, Calogero AE 2020 Next generation sequencing: toward an increase of the diagnostic yield in patients with apparently idiopathic spermatogenic failure. Asian J Androl 22:1-6. DOI: 10.4103/aja.aja_25_20.
71. Mongioì LM, Alamo A, Calogero AE, Compagnone M, Giacone F, Cannarella R, La Vignera S, Condorelli RA 2020 Evaluation of seminal fluid leukocyte subpopulations in patients with varicocele. Int J Immunopathol Pharmacol 34:(in press). DOI: 10.1177/2058738420925719. Scopus 2-s2.0-5087732276. WOS:000551988600001.
72. La Vignera S, Cannarella R, Condorelli RA, Torre F, Calogero AE 2020 Sex-specific SARS-CoV-2 mortality: among hormone-modulated ACE2 expression, risk of venous thromboembolism and hypovitaminosis D. Int J Mol Sci 21:2948. DOI: 10.3390/ijms21082948. Scopus 2-s2.0-85084001718. WOS:000535565300290.
73. Cocchiaro T, Meneghini C, Dal Lago A, Fabiani C, Amodei M, Miriello D, Crisafulli ML, Meneghini C, Capone C, Cannarella R, Condorelli RA, La Vignera S, Calogero AE, Lenzi A, Rago R 2020 Assessment of sexual and emotional distress in infertile couple: validation of a new specific psychometric tool. J Endocrinol Invest 43:1729-1737. DOI: 10.1007/s40618-020-01263-z. Scopus 2-s2.0-85084117979. WOS:000528441700001.
74. Cannarella R, Salemi M, Condorelli RA, Cimino L, Giurato G, Marchese G, Cordella A, Romano C, La Vignera S, Calogero AE 2020 SOX13 gene downregulation in peripheral blood mononuclear cells of patients with Klinefelter syndrome. Asian J Androl 22:1-6. DOI: 10.4103/aja.aja_37_20.
75. Condorelli RA, Barbagallo F, Calogero AE, Cannarella R, Crafa A, La Vignera S 2020 D-chiro-inositol improves sperm mitochondrial function: in-vitro evidence. J Clin Med 9:E1373. DOI: 10.3390/jcm9051373. WOS: 000540223800130.
76. Mongioì LM, Barbagallo F, Condorelli RA, Cannarella R, Aversa A, La Vignera S, Calogero AE 2020 Possible long-term endocrine-metabolic complications in COVID-19: Lesson from the SARS model. Endocrine 68:467-470. DOI: 10.1007/s2020-020-02349-7. 68:467-470. DOI: 10.1007/s12020-020-02349-7. Scopus 2-s2.0-85085965690. WOS:000539645200001.
77. Crafa A, Cannarella R, Condorelli RA, La Vignera S, Calogero AE 2020 Is there an association between vitamin D deficiency and erectile dysfunction? A systematic review and meta-analysis. Nutrients 12:E1411. DOI: 10.3390/nu12051411. Scopus 2-s2.0-85084883857. WOS:000542272700208.
78. Barbagallo F, Condorelli RA, Mongioì LM, Cannarella R, Aversa A, Calogero AE, La Vignera S 2020 Effects of bisphenols on testicular steroidogenesis. Front Endocrinol (in press). DOI: 10.3389/fendo.2020.00373.
79. Cannarella R, Condorelli RA, Calogero AE, La Vignera S 2020 Novel insights on the role of the human sperm proteome. Protein Pept Lett. May 5. DOI: 10.2174/0929866527666200505215921. Online ahead of print.
80. Salemi M, Marchese G, Cordella A, Cannarella R, Barone C, Salluzzo MG, Calogero AE, Romano C 2020 Long non-coding RNA GAS5 expression in patients with Down syndrome. Int J Med Sci 17:1315-1319. DOI 10.7150/ijms.45386. Scopus 2-s2.0-85087473992. WOS:000545935500003.
81. Mongioì LM, Condorelli RA, Alamo A, Cannarella R, Musso N, La Vignera S, Calogero AE 2020 Follicle-stimulating hormone treatment and male idiopathic infertility: Effects on sperm parameters and oxidative stress indices according to FSHR c. 2039 A/G and c. -29 G/A genotypes. J Clin Med 9:1690. DOI: 10.3390/jcm9061690. WOS:000549264500001.
82. La Vignera S, Izzo G, Emerenziani GP, Cannarella R, Condorelli RA, Calogero AE, Aversa A 2020 Male hypogonadism: therapeutic choices and pharmacological management. Minerva Endocrinol 45:189-203. DOI: 10.23736/S0391-1977.20.03195-8. Scopus 2-s2.0-85092501830. WOS:000577261900004.
83. La Vignera S, Condorelli RA, Cannarella R, Cimino L, Mongioì LM, Duca Y, Giacone F, Calogero AE 2020 Does follicle-stimulating hormone really prevent male hypogonadism in infertile patients? Aging Male in press. DOI: 10.1080/13685538.1781807. Scopus 2-s2.0-85087351227.
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84. La Vignera S, Cannarella R, Condorelli RA, Torre F, Aversa A, Calogero AE 2020 SARS-CoV-2: The endocrinological protective clinical model derived from patients with prostate cancer. Ther Adv Endocrinol Metab 11:1-2. DOI: 10.1177/2042018820942385. Scopus 2-s2.0-85087748646. WOS:000552595600001.
85. Cannarella R, Musso N, Condorelli RA, Musmeci M, Stefani S, La Vignera S, Calogero AE 2020 The 2039 A/G FSH receptor gene polymorphism influence glucose metabolism in healthy men. Endocrine 70:629-634. DOI 10.1007/s12020-020-02420-3. Scopus 2-s2.0-85088096097. WOS:000549658400001.
86. Alamo A, De Luca C, Mongioì LM, Barbagallo F, Cannarella R, La Vignera S, Calogero AE, Condorelli RA 2020 Mitochondrial membrane potential predicts 4-hour sperm motility. Biomedicines 8:196. DOI 10.3390/biomedicines.8070196. Scopus 2-s2.0-85089276494. WOS:000557959900001.
87. Barbagallo F, Calogero AE, Cannarella R, Condorelli RA, Mongioì LM, Aversa A, La Vignera S 2020 The testis in patients with CoVID-19: virus reservoir or immunization resource? Transl Androl Urol 9:1897-1900. DOI: 10.21037/tau-20-900.
88. Cannarella R, Condorelli RA, Valiani M, TyuTyusheva N, Calogero AE, La Vignera S, Bertelloni S 2020 Aspetti di prevenzione primaria dell’infertilità maschile. Prospettive in Pediatria 50 (198):135-144.
89. La Vignera S, Condorelli RA, Cimino L, Cannarella R, Giacone F, Calogero AE 2020 Prevenzione primaria dell’infertilità maschile nella pratica clinica. L’Endocrinologo 21:3-6. DOI: 10.1007/s40619-020-00700-8.
90. Crafa A, Condorelli RA, Mongioì LM, Cannarella R, Barbagallo F, Aversa A, Izzo G, Perri A, Calogero AE, La Vignera S 2020 Mean platelet volume as a marker of vasculogenic erectile dysfunction and future cardiovascular risk. J Clin Med 9:2513. DOI: 10.3390/jcm9082513. WOS:000564872500001.
91. Cannarella R, Maniscalchi ET, Condorelli RA, Scalia M, Guerri G, La Vignera S, Bertelli M, Calogero AE 2020 Ultrastructural sperm flagellum defects in a patient with CCDC39 compound heterozygous mutations and primary ciliary dyskinesia/situs viscerum inversus. Front Genet 11:974. DOI: 10.3389/fgene.2020.00974. Scopus 2-s2.0-85090779643. WOS:000570470100001.
92. La Vignera S, Calogero AE, Cannarella R, Condorelli RA, Magagnini C, Aversa A 2020 Obstructive sleep apnea and testosterone replacement therapy. Androgens: Clinical Research and Therapeutics 1.1. DOI: 10.1089/andro.2020.0001.
93. La Vignera S, Aversa A, Cannarella R, Condorelli RA, Duca Y, Russo GI, Calogero AE 2020 Pharmacological treatment of lower urinary tract symptoms in benign prostatic hyperplasia: consequences on sexual function and possible endocrine effects. Expert Opin Pharmacother (in press). DOI: 10.1080/14656566.2020.1817382. Scopus 2-s2.0-85090444586. WOS:000567605000001.
94. Barbagallo F, Mongioì LM, Cannarella R, La Vignera S, Condorelli RA, Calogero AE 2020 Sexual dysfunction in diabetic women: an update on current knowledge. Diabetology 1:11-21. DOI: 10.3390/diabetology1010002.
95. Cannarella R, Musso N, Condorelli RA, Musmeci M, Stefani S, La Vignera S, Calogero AE 2020 Combined effects of the FSHR 2039A/G and FSHR -29G/A polymorphisms on male reproductive parameters. World J Men’s Health (in press). DOI: 10.5534/wjmh.200070. Scopus 2-s2.0-85095681475.
96. Mongioì LM, Cimino L, Condorelli RA, Magagnini MC, Barbagallo F, Cannarella R, La Vignera S, Calogero AE 2020 Effectiveness of a very-low-calorie ketogenic diet on testicular function in overweight/obese men. Nutrients 12:2967. DOI: 10.3390/nu12102967. Scopus 2-s2.0-85091715051. WOS:000585281900001.
97. La Vignera S. Cannarella R, Calogero AE, Condorelli R, Aversa A, La Vignera S 2020 Systemic effects of the hormonal treatment of male hypogonadism with preliminary indications for the management of Covid-19 patients. Ther Adv Endocrinol Metab Metab 11:1-18. DOI: 10.1177/2042018820966438. Scopus 2-s2.0-85092565938. WOS:000581605800001.
98. Cannarella R, Barbagallo F, Crafa A, La Vignera S, Condorelli RA, Calogero AE 2020 Seminal plasma
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transcriptome and proteome: towards a molecular approach in the diagnosis of idiopathic male infertility. Int J Mol Sci 21:7308. DOI: 10.3390/ijms21197308. Scopus 2-s2.0-85091968689.
99. La Vignera S, Cannarella R, Galvano F, Grillo A, Aversa A, Cimino L, Magagnini C, Mongioì LM, Condorelli RA, Calogero AE 2020 The ketogenic diet corrects metabolic hypogonadism and preserves pancreatic ß-cell function in overweight/obese men: a single-arm uncontrolled study. Endocrine (in press). DOI: 10.1007/s12020-020-02518-8. WOS: 000577851900001.
100. Cannarella R, Precone V, Guerri G, Busetto GM, Di Renzo GC, Gerli S, Manara E, Dautaj A, Bertelli M, Calogero AE 2020 Clinical evaluation of a custom gene panel as a tool for precision male infertility diagnosis by next-generation sequencing. Life 10:242. DOI: 10.3390/life10100242. Scopus 2-s2.0-85092710846. WOS:000586152500001.
101. Cannarella R, Condorelli RA, Barbagallo F, Aversa A, Calogero AE, La Vignera S 2020 TSH lowering effects of metformin: a possible mechanism of action. J Endocrinol Invest (in press). DOI: 10.1007/s40618-020-01445-9. Scopus 2-s2.0-85092571333.
102. La Vignera S, Cannarella R, Aversa A, Condorelli RA, Calogero AE 2020 Leukocytospermia in adolescents: possible clinical interpretations. J Endocrinol Invest (in press). DOI: 10.1007/s40618-020-01462-8.
103. Salemi M, Rappazzo G, Ridolfo F, Salluzzo MG, Cannarella R, Castiglione R, Caniglia S, Tirolo C, Calogero AE, Romano C 2020 Cerebellar degeneration-related protein 1 expression in fibroblasts of patients affected by Down syndrome. All Life 13:548-555. DOI: 10.1080/26895293.2020.1832922. Scopus 2-s2.0-85092734991.
104. Calogero AE, Cannarella R 2020 Sindrome metabolica e funzione testicolare nella tarda adolescenza. L’Endocrinologo 21:404-405. DOI: 10.1007/s40619-020-00774-4.
105. Condorelli RA, La Vignera S, Barbagallo F, Alamo A, Mongioì LM, Cannarella R, Aversa A, Calogero AE 2020 Bio-functional sperm parameters: Does age matter? Frontiers in Endocrinology, Section Endocrinology of Aging 11:558374. DOI: 10.3389/fendo.2020.558374.
106. Precone V, Cannarella R, Paolacci S, Busetto G, Beccari T, Stuppia L, Tonini G, Zulian A, Marceddu G, Calogero AE, Bertelli M. Male infertility diagnosis: improvement of genetic analysis performance by the introduction of pre-diagnostic genes in a next-generation sequencing custom-made panel. Front Endocrinol 11:605237. DOI: 10.3389/fendo.2020.605237.
107. Garolla A, Pizzol D, Carosso AR, Borini A, Ubaldi FM, Calogero AE, Ferlin A, Lanzone A, Tomei F, Engl B, Rienzi L, De Santis L, Coticchio G, Smith L, Cannarella R, Anastasi A, Menegazzo M, Stuppia L, Corsini C, Foresta C 2020 Practical clinical and diagnostic pathway for the investigation of the infertile couple. Front Endocrinol (section Reproduction) (5/8/2020). In press.
108. Torre F, Calogero AE, Condorelli RA, Cannarella R, Aversa A, La Vignera S 2020 Contraccezione ormonale e funzione tiroidea. L’Endocrinologo 21:470-474. DOI: 10.1007/s40619-020-00797-x.
109. Cannarella R, Crafa A, Barbagallo F, Mongioì LM, Condorelli RA, Aversa A, Calogero AE, La Vignera S 2020 Seminal plasma proteomic biomarkers of oxidative stress. Int J Mol Sci 21:9113. Section: Molecular Endocrinology and Metabolism – Special Issue on “Oxidative Stress in Metabolic and Endocrine Diseases: Basic and Translational Aspects”. DOI: 10.3390/ijms2129113.
110. Salemi M, Cannarella R, Cimino L, Condorelli RA, Giurato G, Marchese G, Cordella A, Santapaola S, Romano C, La Vignera S, Calogero AE 2020 GPR56 gene down-regulation in patients with Klinefelter syndrome: a candidate for infertility? Minerva Endocrinologica (in press).
111. Alahmar AT, Calogero AE, Singh R, Cannarella R, Sengupta P, Sulagna D 2020 Coenzyme Q10, oxidative stress markers, and sperm DNA damage in men with idiopathic oligoasthenoteratospermia. Clin Exp Reprod Med. In press.
112. De Geronimo V, Cannarella R, La Vignera S. Thyroid Function and Obesity: From Mechanisms to the Benefits
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of Levothyroxine in Obese Patient. Endocr Metab Immune Disord Drug Targets. 2021 Jan 18. doi: 10.2174/1871530321666210118162625. Epub ahead of print. PMID: 33461477.
113. Cannarella R, Calogero AE, Aversa A, Condorelli RA, La Vignera S. Differences in Penile Hemodynamic Profiles in Patients with Erectile Dysfunction and Anxiety. J Clin Med. 2021 Jan 21;10(3):402. doi: 10.3390/jcm10030402. PMID: 33494316; PMCID: PMC7864480.
114. Salemi M, Mazzetti S, De Leonardis M, Giampietro F, Medici V, Poloni TE, Cannarella R, Giaccone G, Pezzoli G, Cappelletti G, Ferri R. Poly (ADP-ribose) polymerase 1 and Parkinson's disease: A study in post-mortem human brain. Neurochem Int. 2021 Mar;144:104978. doi: 10.1016/j.neuint.2021.104978. Epub 2021 Jan 29. PMID: 33516746.
115. Cannarella R, Paganoni AJJ, Cicolari S, Oleari R, Condorelli RA, La Vignera S, Cariboni A, Calogero AE, Magni P. Anti-Müllerian Hormone, Growth Hormone, and Insulin-Like Growth Factor 1 Modulate the Migratory and Secretory Patterns of GnRH Neurons. Int J Mol Sci. 2021 Feb 28;22(5):2445. doi: 10.3390/ijms22052445. PMID: 33671044; PMCID: PMC7957759.
116. Barbagallo F, La Vignera S, Cannarella R, Crafa A, Calogero AE, Condorelli RA. The Relationship between Seminal Fluid Hyperviscosity and Oxidative Stress: A Systematic Review. Antioxidants (Basel). 2021 Feb 27;10(3):356. doi: 10.3390/antiox10030356. PMID: 33673452; PMCID: PMC7997326.
117. Cannarella R, Condorelli RA, Barbagallo F, La Vignera S, Calogero AE. Endocrinology of the Aging Prostate: Current Concepts. Front Endocrinol (Lausanne). 2021 Feb 22;12:554078. doi: 10.3389/fendo.2021.554078. PMID: 33692752; PMCID: PMC7939072.
118. Favilla V, Cannarella R, Trovato F, Li Volti G, Distefano A, Grimaldi E, La Camera G, La Vignera S, Condorelli RA, Calogero AE, Cimino S. Effects of dutasteride on sex hormones and cerebrospinal steroids in patients treated for benign prostatic hyperplasia. Endocrine. 2021 Mar 9. doi: 10.1007/s12020-021-02675-4. Epub ahead of print. PMID: 33751390.
119. Kiani AK, Paolacci S, Calogero AE, Cannarella R, Di Renzo GC, Gerli S, Della Morte C, Busetto GM, De Berardinis E, Del Giudice F, Stuppia L, Facchinetti F, Dinicola S, Bertelli M. From Myo-inositol to D-chiro-inositol molecular pathways. Eur Rev Med Pharmacol Sci. 2021 Mar;25(5):2390-2402. doi: 10.26355/eurrev_202103_25279. PMID: 33755975.
120. Cannarella R, Barbagallo F, Crafa A, Mongioì LM, Aversa A, Greco E, Condorelli RA, LA Vignera S, Calogero AE. Testosterone replacement therapy in hypogonadal male patients with hypogonadism and heart failure: a meta-analysis of randomized controlled studies. Minerva Urol Nephrol. 2021 Mar 29. doi: 10.23736/S2724-6051.21.04307-X. Epub ahead of print. PMID: 33781026.
121. La Vignera S, Crafa A, Condorelli RA, Barbagallo F, Mongioì LM, Cannarella R, Compagnone M, Aversa A, Calogero AE. Ultrasound evaluation of patients with male accessory gland inflammation: a pictorial review. Andrology. 2021 Apr 1. doi: 10.1111/andr.13011. Epub ahead of print. PMID: 33794059.
122. Cannarella R, Condorelli RA, Gusmano C, Barone N, Burrello N, Aversa A, Calogero AE, La Vignera S. Temporal Trend of Conventional Sperm Parameters in a Sicilian Population in the Decade 2011-2020. J Clin Med. 2021 Mar 2;10(5):993. doi: 10.3390/jcm10050993. PMID: 33801210; PMCID: PMC7957883.
123. La Vignera S, Crafa A, Condorelli RA, Barbagallo F, Mongioì LM, Cannarella R, Compagnone M, Aversa A, Calogero AE. Ultrasound aspects of symptomatic versus asymptomatic forms of male accessory gland inflammation. Andrology. 2021 Apr 5. doi: 10.1111/andr.13014. Epub ahead of print. PMID: 33818914.
124. Cannarella R, Calogero AE, Condorelli RA, Greco EA, Aversa A, La Vignera S. Is there a role for glucagon-like peptide-1 receptor agonists in the treatment of male infertility? Andrology. 2021 Apr 5. doi: 10.1111/andr.13015. Epub ahead of print. PMID: 33818920.
125. Perelli S, Calogero AE, Condorelli RA, Cannarella R, Garofalo A, Brescia R, Ciuni R, Greco EA, LA Vignera S. Conservative management of primary hyperparathyroidism in pregnancy. Minerva Endocrinol (Torino). 2021
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Apr 15. doi: 10.23736/S2724-6507.21.03475-8. Epub ahead of print. PMID: 33855389.
126. Cannarella R, Caruso M, Crafa A, Timpanaro TA, Lo Bianco M, Presti S, Condorelli RA, La Vignera S, Calogero AE. Testicular Growth and Pubertal Onset in GH-Deficient Children Treated With Growth Hormone: A Retrospective Study. Front Endocrinol (Lausanne). 2021 Apr 2;12:619895. doi: 10.3389/fendo.2021.619895. PMID: 33868165; PMCID: PMC8050347.

Attività editoriale:

  1. 2017: Membro Associato della Facoltà F1000 Prime, Londra.
  2. Revisore per i seguenti giornali:: Scientific Reports, Sexual Development, The Wold Journal of Men’s Health, Journal of Assisted Reproduction and Genetics, Asian Journal of Andrology, Endocrine Connections, The FEBS Journal, Clinical Case Reports, Investigative and Clinical Urology, Biology Reports, International Journal of Impotence Research.
  3. 2019: Membro dell’Editorial Board della rivista Minerva Endocrinologica (pISSN 0391-1977; eISSN 1827-1634)
  4. 2020: Guest Associate Editor di Reproduction (sezione speciale della rivista Frontiers in Endocrinology), Argomento di ricerca: “Male Idiopathic Infertility: Novel Possible Targets”.
  5. 2020: Guest Editor per la rivista Minerva Endocrinologica, Argomento: “Male Infertility: from etiology to management”.
  6. 2020: Guest Editor per la rivista International Journal of Molecular Science, Argomento: “Molecular Background of Male and Female Central Hypogonadism”.
  7. 2021: Review Editor per l’Editorial Board della rivista Cancer Endocrinology (sezione speciale della rivista Frontiers in Endocrinology and Frontiers in Oncology).
  8. 2020: Guest Editor per la rivista International Journal of Molecular Science, Argomento: “Molecular Background of Male and Female Central Hypogonadism 2.0”.
  9. 2021: Guest Associate Editor di Reproduction (sezione speciale della Frontiers in Endocrinology), Argomento di ricercs: “Disruptors on Males Reproduction---Emerging Risk Factors”.